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1

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

Wang, Jiang, Sánchez-Roselló, María, Aceña, José Luis, del Pozo, Carlos, Sorochinsky, Alexander E., Fustero, Santos, Soloshonok, Vadim A., Liu, Hong

Journal:

Chemical Reviews

Year:

2014

Language:

english

File:

PDF, 11.00 MB

english, 2014

2

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || SF 5 -Synthons: Pathways to Organic Derivatives of SF 6

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.72 MB

english, 2005

3

Fluorine‐Containing Drugs Approved by the FDA in 2018

Mei, Haibo, Han, Jianlin, Fustero, Santos, Medio-Simon, Mercedes, Sedgwick, Daniel M., Santi, Claudio, Ruzziconi, Renzo, Soloshonok, Vadim Anatolievich

Journal:

Chemistry - A European Journal

Year:

2019

Language:

english

File:

PDF, 3.70 MB

english, 2019

4

Synthesis of fluorine-containing compounds under operationally convenient conditions

Vadim A. Soloshonok, Dmitrii O. Berbasov

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 174 KB

english, 2004

5

Operationally convenient asymmetric synthesis of (S)- and (R)-3-amino-4,4,4-trifluorobutanoic acid: Part II. Enantioselective biomimetic transamination of 4,4,4-trifluoro-3-oxo-N-[(R)-1-phenylethyl]butanamide

Vadim A. Soloshonok, Hironari Ohkura, Manabu Yasumoto

Journal:

Journal of Fluorine Chemistry

Year:

2006

Language:

english

File:

PDF, 274 KB

english, 2006

6

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Regioexhaustive Functionalizations: To Miss an Isomer Means to Miss a Chance

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.52 MB

english, 2005

7

Chiral sulfoxides: advances in asymmetric synthesis and problems with the accurate determination of the stereochemical outcome

Han, Jianlin, Soloshonok, Vadim A., Klika, Karel D., Drabowicz, Józef, Wzorek, Alicja

Journal:

Chemical Society Reviews

Year:

2018

Language:

english

File:

PDF, 3.14 MB

english, 2018

8

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Zhu, Yi, Han, Jianlin, Wang, Jiandong, Shibata, Norio, Sodeoka, Mikiko, Soloshonok, Vadim A., Coelho, Jaime A. S., Toste, F. Dean

Journal:

Chemical Reviews

Year:

2018

Language:

english

File:

PDF, 27.58 MB

english, 2018

9

ChemInform Abstract: Biomimetic Transamination of α-Keto Perfluorocarboxylic Esters. An Efficient Preparative Synthesis of β,β,β- Trifluoroalanine.

V. A. SOLOSHONOK, V. P. KUKHAR

Journal:

Year:

1997

File:

PDF, 30 KB

1997

10

Biomimetic base-catalyzed [1,3]-proton shift reaction. A practical synthesis of β-fluoroalkyl-β-amino acids

Vadim A. Soloshonok, Valery P. Kukhar

Journal:

Year:

1996

Language:

english

File:

PDF, 758 KB

english, 1996

11

Chemo-enzymatic approach to the synthesis of each of the four isomers of α-alkyl-β-fluoroalkyl-substituted β-amino acids

Vadim A. Soloshonok, Alexander G. Kirilenko, Nataly A. Fokina, Valery P. Kukhar, Sergey V. Galushko, Vytas K. Švedas, Giuseppe Resnati

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 294 KB

english, 1994

12

Biocatalytic approach to enantiomerically pure β-amino acids

Vadim A. Soloshonok, Nataly A. Fokina, Antonyna V. Rybakova, Irine P. Shishkina, Sergey V. Galushko, Alexander E. Sorochinsky, Valery P. Kukhar, Mariya V. Savchenko, Vytas K. Švedas

Journal:

Tetrahedron: Asymmetry

Year:

1995

Language:

english

File:

PDF, 666 KB

english, 1995

13

Synthesis of highly 1,3-proton shift transferable N-benzyl imines of trifluoroacetophenone under the “low-basicity” reaction conditions

Dmitrii O Berbasov, Ifeyinwa D Ojemaye, Vadim A Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

14

Fluorine chemistry in Ukraine

Yurii L. Yagupolskii, Vadim A. Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

15

Convenient synthesis of fluoroalkyl α- and β-aminophosphonates

Gerd-Volker Röschenthaler, Valery P. Kukhar, Irene B. Kulik, Alexander E. Sorochinsky, Vadim A. Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

16

Electrochemical fluorination of 1-ethylpiperazine and 4-methyl- and/or 4-ethylpiperazinyl substituted carboxylic acid methyl esters

Takashi Abe, Hajime Baba, Irina Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2001

Language:

english

File:

PDF, 332 KB

english, 2001

17

2,2,2-Trifluoro-1-(1-adamantyl)ethylamine hydrochloride

A.G. Yurchenko, T.V. Fedorenko, V.P. Tikchonov, V.A. Soloshonok, V.P. Kukhar'

Journal:

Journal of Fluorine Chemistry

Year:

1992

Language:

english

File:

PDF, 302 KB

english, 1992

18

Electrochemical fluorination of several 1,4-bis[(methoxycarbonyl)alkyl] substituted piperazines

Takashi Abe, Hajime Baba, Irina Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2001

Language:

english

File:

PDF, 270 KB

english, 2001

19

Electrochemical fluorination of (N,N-dialkylamino)alcohols

Takashi Abe, Haruhiko Fukaya, Eiji Hayashi, Taizo Ono, Masakazu Nishida, Irina Soloshonok, Kunio Okuhara

Journal:

Journal of Fluorine Chemistry

Year:

1999

Language:

english

File:

PDF, 237 KB

english, 1999

20

Electrochemical fluorination of di- and tri-(2-hydroxyethyl)-substituted alkylamines

Takashi Abe, Irina Soloshonok, Hajime Baba, Akira Sekiya

Journal:

Journal of Fluorine Chemistry

Year:

1999

Language:

english

File:

PDF, 182 KB

english, 1999

21

Regioselective Oxyfunctionalization of Bridgehead Adamantane Derivatives

Alexander E Sorochinsky*, Alexander A Petrenko, Vadim A Soloshonok*, Giuseppe Resnati

Journal:

Year:

1997

Language:

english

File:

PDF, 785 KB

english, 1997

22

Biomimetic transamination of α-keto perfluorocarboxylic esters. An efficient preparative synthesis of β,β,β-trifluoroalanine

Vadim A Soloshonok, Valery P Kukhar

Journal:

Year:

1997

Language:

english

File:

PDF, 488 KB

english, 1997

23

Transamination of fluorinated β-keto carboxylic esters. A biomimetic approach to β-polyfluoroalkyl-β-amino acids.

Vadim A. Soloshonok, Alexander G. Kirilenko, Valery P. Kukhar', Giuseppe Resnati

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 253 KB

english, 1993

24

Convenient, large-scale asymmetric synthesis of β-aryl-substituted α,α-difluoro-β-amino acids

Vadim A Soloshonok, Hironari Ohkura, Alexander Sorochinsky, Natalia Voloshin, Andrey Markovsky, Michael Belik, Takashi Yamazaki

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 77 KB

english, 2002

25

Synthesis of optically pure (R)- and (S)-α-trifluoromethyl-alanine

Pierfrancesco Bravo, Silvia Capelli, Stefano Valdo Meille, Fiorenza Viani, Matteo Zanda, Valery P. Kukhar, Vadim A. Soloshonok

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 748 KB

english, 1994

26

Reactions of perfluorocarbonyl compounds with 1,3,3-trimethyl-2-methyleneindoline

S. V. Pazenok, V. A. Soloshonok, L. M. Yagupol'skii

Journal:

Chemistry of Heterocyclic Compounds

Year:

1990

Language:

english

File:

PDF, 71 KB

english, 1990

27

Biocatalytic resolution of β-fluoroalkyl-β-amino acids

Vadim A. Soloshonok, Alexander G. Kirilenko, Nataly A. Fokina, Irine P. Shishkina, Sergey V. Galushko, Valery P. Kukhar, Vytas K. Švedas, Elena V. Kozlova

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 612 KB

english, 1994

28

Thermal 1,3-proton shift reaction and its application for operationally convenient and improved synthesis of α-(trifluoromethyl)benzylamine

Manabu Yasumoto, Hisanori Ueki, Vadim A. Soloshonok

Journal:

Journal of Fluorine Chemistry

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

29

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || A New Aspect of Fluoroalkylated Acetylenes: Synthesis and Applications—Hydrometallation and Carbometallation

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.49 MB

english, 2005

30

Asymmetric synthesis of phosphonotrifluoroalanine and its derivatives using N-tert-butanesulfinyl imine derived from fluoral

Gerd-Volker Röschenthaler, Valery P. Kukhar, Irine B. Kulik, Michael Yu. Belik, Alexander E. Sorochinsky, Eduard B. Rusanov, Vadim A. Soloshonok

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 281 KB

english, 2012

31

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Functional Compounds Based on Hypervalent Sulfur Fluorides

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.85 MB

english, 2007

32

Biomimetic Reductive Amination of Fluoro Aldehydes and Ketones via [1,3]-Proton Shift Reaction.1 Scope and Limitations

Ono, Taizo, Kukhar, Valery P., Soloshonok, Vadim A.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 323 KB

english, 1996

33

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Stereoselective Synthesis of Polyfluorinated Exo -Tricyclononenes and Norbornenes

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.80 MB

english, 2007

34

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Cationic Cyclizations of Fluoro Alkenes: Fluorine as a Controller and an Activator

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

35

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Synthesis of Novel gem -Difluorinatedcyclopropane Hybrids: Applications for Material and Medicinal Sciences

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 983 KB

english, 2007

36

[ACS Symposium Series] Current Fluoroorganic Chemistry Volume 949 (New Synthetic Directions, Technologies, Materials, and Biological Applications) || Synthesis of gem -Difluoromethylated Sugar Nucleosides

Soloshonok, Vadim A., Mikami, Koichi, Yamazaki, Takashi, Welch, John T., Honek, John F.

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

37

Practical synthesis of fluorine-containing α- and β-amino acids: recipes from Kiev, Ukraine

Kukhar, Valery P, Sorochinsky, Alexander E, Soloshonok, Vadim A

Journal:

Future Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

38

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Fluoroform, Fluoral, Trifluoroacetic, and Trifluoromethanesulfinic Acids Derivatives as New Reagents for the Introduction of Polyfluorinated Moieties

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.06 MB

english, 2005

39

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || New Nucleophilic Fluoroalkylation Chemistry

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.90 MB

english, 2005

40

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Functional Group Transformations at α-Carbon to Trifluoromethyl Group

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.04 MB

english, 2005

41

New asymmetric approach to β-trifluoromethyl isoserines

Shevchuk, Michael V., Kukhar, Valery P., Röschenthaler, Gerd-Volker, Bassil, Bassem S., Kawada, Kosuke, Soloshonok, Vadim A., Sorochinsky, Alexander E.

Journal:

Year:

2013

Language:

english

File:

PDF, 398 KB

english, 2013

42

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Fluorine-Based Crystal Engineering

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.96 MB

english, 2005

43

Preface

Fustero, Santos, del Pozo, Carlos, Soloshonok, Vadim A., Aceña, José Luis

Journal:

Journal of Fluorine Chemistry

Year:

2013

Language:

english

File:

PDF, 315 KB

english, 2013

44

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Recent Advances in Perfluoroalkylation Methodology

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.66 MB

english, 2005

45

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Haloperfluorocarbons: Versatile Tectons in Halogen Bonding Based Crystal Engineering

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 3.38 MB

english, 2005

46

Optical Purifications via Self-Disproportionation of Enantiomers by Achiral Chromatography: Case Study of a Series of α-CF 3 -containing Secondary Alcohols

Sorochinsky, Alexander E., Katagiri, Toshimasa, Ono, Taizo, Wzorek, Alicja, Aceña, José Luis, Soloshonok, Vadim A.

Journal:

Year:

2013

Language:

english

File:

PDF, 119 KB

english, 2013

47

Chemical deracemization and (S) to (R) interconversion of some fluorine-containing α-amino acids

Sorochinsky, Alexander E., Ueki, Hisanori, Aceña, José Luis, Ellis, Trevor K., Moriwaki, Hiroki, Sato, Tatsunori, Soloshonok, Vadim A.

Journal:

Journal of Fluorine Chemistry

Year:

2013

Language:

english

File:

PDF, 366 KB

english, 2013

48

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Synthetic Methods for the Preparation of Ring-Fluorinated Heterocycles via Intramolecular Vinylic Substitution of gem -Difluoroalkenes

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.48 MB

english, 2005

49

Convenient Asymmetric Synthesis of β-Substituted α,α-Difluoro-β-amino Acids via Reformatsky Reaction between Davis' N -Sulfinylimines and Ethyl Bromodifluoroacetate

Sorochinsky, Alexander, Voloshin, Natalia, Markovsky, Andrey, Belik, Michael, Yasuda, Nobuhiro, Uekusa, Hidehiro, Ono, Taizo, Berbasov, Dmitrii O., Soloshonok, Vadim A.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

50

[ACS Symposium Series] Fluorine-Containing Synthons Volume 911 || Asymmetric Synthesis of Monofluorinated Compounds Having the Fluorine Atom Vicinal to π-Systems

Soloshonok, Vadim A.

Year:

2005

Language:

english

File:

PDF, 1.56 MB

english, 2005

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